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Devils Claw
Devil’s claw root
Other Names Devil’s claw root is the common name for the tubers of Harpogophytum procumbens.
What Is It? Devil’s claw is an herbacious African perennial plant, native to the Kalahari savanna of Southern Africa, the Namibian steppes, and Madagascar. [ii] The plant lies flat on the ground, with long branches which extend to 1.5 metres in length. [iii] Devil’s claw root refers to the dried, secondary tubers of the plant, which are used medicinally, primarily in Africa and Europe. [iv] According to ESCOP the roots should contain not less than 1.0% of the compound harpagoside. [v] Devil’s claw root plays a valuable role in African folk medicine, where it has been used as a digestive tonic, for blood disorders, to reduce fever, as an analgesic, and to relieve various complaints during pregnancy. [vi]
Devil’s claw root has been the subject of analysis into its constituents, animal and human studies. [vii] Devil’s claw root is available in dried natural form for tea, or in capsules, tablets, fluid extracts and ointments. The herb is most popularly used to relieve arthritis. [viii] Topical preparations of Devil’s claw root are applied to sores, ulcers, boils and skin lesions. [ix]
Medicinal History In its origins in South Africa, Devil’s claw root was used for fever, stomach upsets and rheumatic disorders. [x] Its bitterness drew attantion to its usefulness for general digestive complaints. [xi] The root was also employed by African women to alleviate pain during pregnancy. [xii] Devil’s claw root was introduced to Western medicine by a South African farmer, G.H. Mehnert, who observed its broad uses among natives. [xiii] Devil’s claw root was first used in Europe in 1953, where it has enjoyed use for arthritic, liver, bile, kidney and bladder complaints, and allergies. [xiv]
Today Devils’ claw root is approved by Germany’s Commission E for loss of appetite, dyspepsia (indigestion), and supportive therapy of disorders of the locomotor system. [xv] It is approved by ESCOP for Painful arthrosis, tendinitis, loss of appetite and dyspepsia. [xvi]
The most popular contemporary use for devil’s claw root is to relieve arthritis. Today in France Devil’s claw root products can be marketed with a claim for traditional use for symptomatic relief of painful joint disorders. [xvii]
Habitat & Cultivation Devil’s claw is a wild-collected plant native to the Kalahari savanna of Southern Africa, the Namibian steppes, and Madagascar. [xviii] The plant enjoys sandy soil and direct sun, and minimum temperatures of 41ø F. The tubers are removed during the plant’s dormant period. [xix] They are cut into sections after harvest and are dried. The slices are then used to make Devil’s claw root preparations. [xx]
How It Works Devil’s claw root contains a group of compounds called the iridoid glucosides, which include harpagoside, and are antiinflammatory. [xxi] The root contains several other anti-inflammatory compounds as well. Other agents in devil’s claw root, inclduing flavonoids and phytosterols, are antioxiant, choleretic (stimulate bile production) and antispasmodic. [xxii] [xxiii] The combination of antiinflammatory, antispasmodic and digestion-enhancing agents supports the uses of devil’s claw for those purposes.
Contemporary Uses Approved by Authoritative Bodies Germany’s Commission E approves the use of Devil’s claw root for:
ESCOP approves the use of Devil’s claw root for:
Potential Risks Safety issues and concerns
Contraindications – based on conditions and medication intake, etc.
Potentially harmful drug interactions
Allergy precautions
Usage Tips According to Germany’s Commission E,
Product Choosing/Buying Tips
Science Update
Devil’s Claw Root helps muscular pain. A study reported in 2001 was performed on patients with slight to moderate muscular tension or slight muscular pain of the back, shoulder and neck. On a double-blind randomised basis, a total of 31 patients received doses of Devil’s claw root extract twice daily, and 32 received a placebo. The duration of the therapy was 4 weeks. A highly significant clinical efficacy was achieved with Devil’s claw extract in cases of slight to moderate muscular pain. [xxxiv]
Devil’s claw review proves positive. In an 1999 published analysis of several Devil’s claw root studies, extracts of the secondary tubers of Devil's Claw (Harpagophytum procumbens) proved valuable for the supportive treatment of degenerative painful rheumatism. Use of devil’s claw extract improved motility and a reduction of pain sensation in several clinical studies. Pharmacological experiments have shown analgesic, antiphlogistic and antiinflammatory actions. [xxxv]
Controversies There are no particular controversies concerning Devil’s claw root.
Fun Facts/Trivia
[i] Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, 2nd ed., (New York: John Wiley & Sons, Inc. 1996). 208
[ii] Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, 2nd ed., (New York: John Wiley & Sons, Inc. 1996). 208
[iii] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 248
[iv] Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, 2nd ed., (New York: John Wiley & Sons, Inc. 1996). 208
[v] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[vi] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 249
[vii] Blumenthal M, Goldberg A, Brinckmann J (eds). Herbal Medicine: Expanded Commission E Monographs. 1st ed., (Newton, MA: Integrative Medicine Communications. 2000). 85
[viii] Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, 2nd ed., (New York: John Wiley & Sons, Inc. 1996). 209
[ix] Blumenthal M, Goldberg A, Brinckmann J (eds). Herbal Medicine: Expanded Commission E Monographs. 1st ed., (Newton, MA: Integrative Medicine Communications. 2000). 85
[x] Samuelsson, Gunnar., Drugs of Natural Origin. 3rd ed., (Stockholm, Swedish Pharmaceutical Press, 1992) 153
[xi] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 249
[xii] Tyler, Varro., Brady, Lynn., Robbers, James., Pharmacognosy. 9th ed., (Philadelphia, Lea & Febiger, 1988) 470
[xiii] Bown, Deni. The Herb Society Of America Encyclopedia of Herbs & Their Uses. (1st ed., (New York: Dorling Kindersley,1995). 291
[xiv] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 249
[xv] Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds.). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. S. Klein, R.S. Rister (trans.). 1st ed., (Austin, TX: American Botanical Council. 1998). 120
[xvi] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xvii] Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd ed., (Paris: Lavoisier Publishing 1993). 487
[xviii] Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics, 2nd ed., (New York: John Wiley & Sons, Inc. 1996). 208
[xix] Bown, Deni. The Herb Society Of America Encyclopedia of Herbs & Their Uses. (1st ed., (New York: Dorling Kindersley,1995). 291
[xx] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 248
[xxi] Blumenthal M, Goldberg A, Brinckmann J (eds). Herbal Medicine: Expanded Commission E Monographs. 1st ed., (Newton, MA: Integrative Medicine Communications. 2000). 85
[xxii] Agricultural Research Service, Dr. Duke’s Phytochemical and Ethnobotanical Databases. http://www.ars-grin.gov/duke/
[xxiii] Bradley PR (ed.). British Herbal Compendium Volume 1: A Handbook of Scientific Information on Widely Used Plant Drugs. 1st ed., (Dorset, England: British Herbal Medicine Association. 1992). 78
[xxiv] Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds.). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. S. Klein, R.S. Rister (trans.). 1st ed., (Austin, TX: American Botanical Council. 1998). 120
[xxv] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xxvi] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xxvii] Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds.). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. S. Klein, R.S. Rister (trans.). 1st ed., (Austin, TX: American Botanical Council. 1998). 120
[xxviii] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xxix] Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds.). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. S. Klein, R.S. Rister (trans.). 1st ed., (Austin, TX: American Botanical Council. 1998). 120
[xxx] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xxxi] Blumenthal M, Busse W, Goldberg A, Gruenwald J, Hall T, Riggins CW, Rister RS (eds.). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. S. Klein, R.S. Rister (trans.). 1st ed., (Austin, TX: American Botanical Council. 1998). 120
[xxxii] Wichtl M, Bisset NG (eds.). Herbal Drugs and Phytopharmaceuticals. Trans from 2nd German ed., (Stuttgart: Medpharm GmbH Scientific Publishers. 1994). 249
[xxxiii] European Scientific Cooperative on Phytotherapy. ESCOP Monographs on the Medicinal Uses of Plant Drugs. 1st ed., (Exeter, U.K.: ESCOP 1997). Fascicule 2
[xxxiv] Gobel H, Heinze A, Ingwersen M, Niederberger U, Gerber D “Effects of Harpagophytum procumbens LI 174 (devil's claw) on sensory, motor und vascular muscle reagibility in the treatment of unspecific back pain” Schmerz 2001 Feb 15:1 10-8
[xxxv] Wegener T Wien “Therapy of degenerative diseases of the musculoskeletal system with South African devil's claw (Harpagophytum procumbens DC)” Med Wochenschr 1999 149:8-10 254-7 |
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